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The Health Protection Agency has reported a continuing increase in whooping cough cases. 665 laboratory confirmed cases of whooping cough have been reported to the HPA in England and Wales between January and March 2012, compared to total of 1,040 cases across the whole of 2011. The increase – continuing from the second half of 2011 - has been reported across all regions in England with some areas reporting clusters in schools, universities and healthcare settings.